This medicine is also sometimes given off-label to help the following conditions: Also, let your doctor know if you drink large amounts of alcohol before starting on this medicine. Your doctor will probably want to order frequent tests to check your body's response to chloroquine. What are side effects of hydroxychloroquine How does plaquenil affect sleep Chloroquine resazurin assay results Usual Adult Dose for Malaria Prophylaxis. Suppression 400 mg 310 mg base orally on the same day every week Comments-Suppressive therapy should begin 2 weeks prior to exposure; however, failing this, an initial dose of 800 mg 620 mg base may be taken in 2 divided doses 6 hours apart. Non-chloroquine-resistant. 1 g 600 mg base PO, THEN; 500 mg 300 mg base PO 6-8 hours later, THEN; 500 mg 300 mg base PO at 24 hours & 48 hours after initial dose; Amebiasis, Extraintestinal. 1 g 600 mg base PO qDay for 2 days, THEN. 500 mg 300 mg base qDay for 14-21 days. Porphyria Cutanea Tarda Off-label 125-250 mg 75-150 mg base PO twice weekly This represents a total dose of 2.5 g chloroquine phosphate or 1.5 g base in three days. The dosage for adults of low body weight and for infants and children should be determined as follows First dose 10 mg base per kg but not exceeding a single dose of 600 mg base. Let your healthcare provider know if your symptoms either don't improve or worsen while taking this medicine. Keep all appointments with your doctor and laboratory. Chloroquine prophylaxis dosage Chloroquine - LiverTox - NCBI Bookshelf, Aralen, Chloroquine phosphate chloroquine dosing. Hydroxychloroquine and skin discolorationPlaquenil increased heart rateHydroxychloroquine annual monitoring Prophylaxis against Chloroquine-sensitive Plasmodium species Prophylaxis against Chloroquine-sensitive Plasmodium species Adult Dose The dosage for prophylaxis is 500 mg = 300 mg base administered once per week on exactly the same day of each week. Chloroquine - FDA prescribing information, side effects.. Aralen Chloroquine Uses, Dosage, Side Effects.. Medicines for the Prevention of Malaria While Traveling.. What Is the Chloroquine Dosage for Preventing Malaria? The usual dosage for malaria prevention in adults is 500 mg once a week. The chloroquine dose in children is based on the child's weight. Children either receive about 8.3 mg per kg of body weight about 3.8 mg per pound of body weight or the adult dose, whichever is less. Dose equivalence and conversion. Doses expressed as chloroquine base. Each tablet contains 155 mg of chloroquine base equivalent to 250 mg of chloroquine phosphate. Syrup contains 50 mg/5 mL of chloroquine base equivalent to 80 mg/5 mL of chloroquine phosphate. The excretion of chloroquine and the major metabolite, desethylchloroquine, in breast milk was investigated in 11 lactating mothers following a single oral dose of chloroquine 600 mg basemaximum daily dose of the drug that the infant received from breast-feeding was about 0.7% of the maternal start dose of the drug in malaria chemotherapy.