Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take hydroxychloroquine with all of your drugs and health problems. Rosuvastatin and hydroxychloroquine Hydroxychloroquine eye floater Moderate Alcohol Use Could Be Safe with Methotrexate for RA. NEW YORK Reuters Health—In patients taking methotrexate for rheumatoid arthritis RA, moderate alcohol consumption – that is, no higher than existing U. K. guidelines for the general population – was not associated with an increased risk of transaminitis, researchers say. There's no known interaction between alcohol and hydroxychloroquine. However, if you're also taking methotrexate you should keep well within the recommended limits no more than 14 units of alcohol per week for adults as methotrexate can interact with alcohol and affect your liver. In some circumstances your doctor may advise lower limits. We compare the side effects and drug effectiveness of Plaquenil and Methotrexate. The study is created by eHealthMe based on reports of 385,604 people who take Plaquenil and Methotrexate, and is updated regularly. eHealthMe has been monitoring drugs since 2008. Our original studies are referenced on 600+ peer-reviewed medical publications. For all uses of hydroxychloroquine: WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Do not start, stop, or change the dose of any drug without checking with your doctor. Methotrexate plaquenil alcohol Does anyone take methotrexate and hydroxychloroquine. - NRAS, Hydroxychloroquine Side-effects, uses, time to work Plaquenil peakPlaquenil oct imagePlaquenil anxiety side effectDoes plaquenil have life long effects If you aren’t responding to methotrexate after a two-month period, your rheumatologist may try some kind of combination therapy, such as adding sulfasalazine and hydroxychloroquine called triple therapy or adding a biologic drug such as etanercept Enbrel, adalimumab Humira, or infliximab Remicade. Common Questions About Taking Methotrexate for Rheumatoid.. Plaquenil vs. Methotrexate side effect and effectiveness comparison.. Methotrexate vs Plaquenil Comparison -. Hydroxychloroquine is a prescription drug. It comes as an oral tablet. Hydroxychloroquine is available as the brand-name drug Plaquenil. It’s also available in a generic version. Methotrexate is a disease-modifying anti-rheumatic drug DMARD that is used to reduce the swelling and pain associated with certain diseases like rheumatoid arthritis, psoriatic arthritis, vasculitis, juvenile arthritis and lupus. More and more doctors are using methotrexate to treat lupus when antimalarials like hydroxychloroquine Plaquenil or nonsteroidal anti-inflammatory drugs aren’t. Low blood sugar has happened with hydroxychloroquine. Sometimes, this has been very bad and could be life-threatening. Talk with the doctor. Check your blood sugar as you have been told by your doctor. Talk with your doctor before you drink alcohol. Low blood cell counts have happened with hydroxychloroquine.