It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Corneal pics chloroquine side effects Drugs for ra plaquenil and Natural resources to make chloroquine Stop guessing how long marijuana, cocaine and most other drugs actually stay in your system. Marijuana is up to 60 days! With Plaquenil, however, the most commonly prescribed anti-malarial, this sort of damage occurs only in 1 out of 5,000 people who take the drug for five years or more. For this reason though, it is important that you see an ophthalmologist for an exam before starting to take an anti-malarial medication for your lupus. Mark a calendar to help you remember. This drug is usually started 2 weeks before entering the area with malaria. Take it once weekly while in the area, and continue taking it for 4 to 8 weeks after leaving the area or as directed by your doctor. To treat malaria, follow your doctor's instructions. Today, it is used to treat rheumatoid arthritis, some symptoms of lupus, childhood arthritis (or juvenile idiopathic arthritis) and other autoimmune diseases. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. How long will plaquenil stay in your system Bone Joint Muscle - Arthritis how long for plaquenil rash to end, Treating Lupus with Anti-Malarial Drugs Johns Hopkins Lupus. Plaquenil for slePlaquenil and gerd First, my mother and sister took plaquenil for lupus with good effect, so I am not just disliking it for no good reason. I also suffer from disabling bipolar disorder. For 25 years, I have gotten hypomanic during spring. Very happy, never depressed. When I started taking Plaquenil, I got a bit depressed but that's not a big deal. PLAQUENIL Side Effects, Reviews by Patients -. Plaquenil Oral Uses, Side Effects, Interactions, Pictures, Warnings.. Plaquenil -. Plaquenil is supposed to stay in your system for 1-2 months after you stop taking it. Try to rest, stay hydrated and away from sick ppl for now and hopefully you will not have any issues ranin02 I say this because Plaquenil has a chemical half-life of 30-60 days you can confirm this on wiki or RX info on the drug--so it takes a LONG time to get out of your system.long for you to notice changes in days. If you remember, most wait at least 3 months before they even see any improvement. For an official answer, I suggest you speak to your doctor or pharmacist. My guess is, because it takes time to build up in your system and because you can reap the benefits of the injections for 1-2 months after you stop treatment, Ithat it extends beyond that time frame.