She suffered from Sjogren syndrome and inflammatory arthritis and was currently treated with prednisone and methotrexate. She was previously treated with hydroxychloroquine (Plaquenil) 200mg bid (6.5mg/kg) for 10 years, which was stopped one year prior to presentation. Pharmacokinetics of chloroquine Side effects plaquenil 200 mg Plaquenil is the devil! Worked well 1st 2 mts. After that I had issues with my vision, felt waves of nervousness, and extreme anxiety where I started to question my sanity. Hallucinated, broke out in rashes and crying spells. With all of the physical and emotional complications that lupus can cause, it’s easy to overlook symptoms that seem minor at first. But take this advice Don’t ignore changes in vision. While side effects of corticosteroids are usually to blame, there is also the possibility of ocular damage associated with long-term use of the antimalarial drugs hydroxychloroquine brand name Plaquenil® and chloroquine. Aug 14, 2017 Signs of retinal damage include blurry or distorted vision, flashes of light or floaters, or loss of night vision. Retinal damage may not improve even after Plaquenil is discontinued. Dilated eye exams should be done every six months to check for retinal problems. Review of systems: Blurred vision, halos, dry eye, dry mouth, gastroesophageal reflux, joint pain Pupils: Reactive to light in each eye from 5 mm in the dark to 2 mm in the light. Extraocular movements: Full, both eyes (OU) Confrontation visual fields: Full OU Intra-ocular pressure The optic nerves appeared healthy with a 0.3 cup-to-disc ratio. Past Ocular History: None Medical History: Sjogren syndrome and inflammatory arthritis, supraventricular tachycardia, anxiety, depression, peptic ulcer disease Medications: prednisone, methotrexate, amitriptyline, ranitidine, estradiol, tizanidine, diltiazem, Restasis Allergies: codeine, droperidol Family History: heart disease, arthritis, cancer Social History: occasional alcohol but no tobacco or intravenous drug use. Symptoms of retinal damage from plaquenil Retinal detachment - Symptoms and causes - Mayo Clinic, Protecting your eyesight when taking Plaquenil Lupus. Hydroxychloroquine method of action arthritisWill plaquenil stop hair lossHydroxychloroquine 200 mg does it have steroids in it Feb 19, 2020 Tell your doctor if you experience serious side effects of Plaquenil including. muscle weakness, twitching, uncontrolled movement, loss of balance or coordination, blurred vision, light sensitivity, seeing halos around lights, Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses. Long-Term Side Effects of Plaquenil for Rheumatoid Arthritis.. Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus. After six weeks on Hydroxychloroquine he got hundreds of black floaters in his eye, with intermittent flashes of light. We went to Addenbrooke's Hospital Casualty where the Casualty Doctor felt he'd had a retinal bleed due to the drug and were referred to the Eye Clinic as an emergency. Stopped prior to retinal pigment epithelial damage or bull’s eye maculopathy, retinal findings may remain stable without progression5. In addition, most patients with retinal toxicity have no visual symptoms until severe damage is done. Therefore early screening is essential. New objective screening modalities including spectral domain optical Hydroxychloroquine is an effective and relatively safe drug that can cause retinal toxicity in a minority of patients. Early diagnosis is important to stop treatment and prevent possible further damage.