It is used to prevent and treat acute attacks of malaria. It is also used to treat discoid or systemic lupus erythematosus and rheumatoid arthritis in patients whose symptoms have not improved with other treatments. Eye screening tests for plaquenil guidelines Plaquenil and cirrhosis Cyclosporine and plaquenil Hydroxychloroquine is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Important information. Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Compared with focal ERG, mfERG is more appropriate for the evaluation of chloroquine and/or hydroxychloroquine toxicity because it generates local ERG responses topographically across the posterior pole and can document a parafoveal or extramacular depression in early retinopathy or bull's eye distribution of ERG depression in late stages. At this point, full-field ERG should be considered to exclude diffuse photoreceptor loss. SUMMARY. Hydroxychloroquine is an effective and relatively safe drug that can cause retinal toxicity in a minority of patients. Early diagnosis is important to stop treatment and prevent possible further damage. Hydroxychloroquine comes as a tablet to take by mouth. This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information. Hydroxychloroquine erg Chloroquine and Hydroxychloroquine Toxicity Workup., Chloroquine and Hydroxychloroquine Toxicity Workup Approach. Plaquenil toxicity first screeninHydroxychloroquine lupus erythematosusDoxycycline and plaquenil interactionsMissed dose of plaquenilHydroxychloroquine price increase 2016 ERG findings in patients using hydroxychloroquine. Tzekov RT1, Serrato A, Marmor MF. Author information 1Department of Ophthalmology, Stanford University Medical Center, Stanford, CA 94305-5308, USA. ERG findings in patients using hydroxychloroquine.. Retinal Physician - Hydroxychloroquine Maculopathy An Update.. Hydroxychloroquine Side Effects Common, Severe, Long Term.. Multifocal ERG ring ratios reveal retinal toxicity in a surprisingly large fraction of patients taking hydroxychloroquine who are referred for evaluation and have no previous history of eye disease. We find the use of ring ratios to be a sensitive measure of dysfunction in ocular hydroxychloroquine toxicity. Diagnosis Hydroxychloroquine-induced retinal toxicity Discussion. Chloroquine CQ and hydroxychloroquine Plaquenil HCQ have been used for many years, initially for the treatment of malaria but now more commonly for the treatment of inflammatory diseases such as rheumatoid arthritis and lupus 1. Multifocal ERG has the ability to detect early macular dysfunction, so it should be included as part of baseline screening. A maximum daily dose of Plaquenil of 5.0mg/kg real weight is recommended. Communication with the prescribing physician is also key to proper treatment and management of your patient.