One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine (Plaquenil), a chloroquine derivative. It is used to treat many diseases including malaria, rheumatoid arthritis and systemic lupus erythematosus. Taking plaquenil while having infections What is the lowest dose of plaquenil Plaquenil lyme herx Plaquenil induced retinal toxicity is reversible if detected early and plaquenil dosage altered or the medication discontinued. Even suspicious early plaquenil toxicity warrants communication with the patient’s treating physician, and meaningful coordination of care would include a report even if the findings are normal. Uploaded on Dec 6, 2016. Last modified by Caroline Bozell on Dec 7, 2016.; Rating Appears in Miscellaneous Condition/keywords plaquenil toxicity Description 70-year-old woman with history of plaquenil use for rheumatoid arthritis. Spectral Domain Optical Coherence Tomography SD OCT uses light to capture micrometer-resolution, three-dimensional images from within optical scattering media. Multifocal Electroretinopathy measures electrical responses of various cell types in the retina. it is the photoreceptors that are the targets of hydroxychloroquine toxicity. It is imperative that patients and physicians are aware of and watch for this drug’s ocular side effects. Retinal toxicity from hydroxychloroquine is rare, but even if the medication is discontinued, vision loss may be irreversible and may continue to progress. Oct images of plaquenil toxicity Retina Today - Imaging in Hydroxychloroquine Toxicity., Plaquenil Toxicity OCT - Retina Image Bank Chloroquine phosphate invertsHow does plaquenil affect sleepChloroquine and malaria Novel Image Analysis Platform May Detect Early Signs of Retinal Toxicity Secondary to Hydroxychloroquine Use. Ellipsoid zone mapping, a new image visualization/analysis platform on optical coherence tomography, may be an effective screening tool to identify subtle retinal changes indicative of toxicity from hydroxychloroquine treatment, Cleveland Clinic research indicates. Novel Image Analysis Platform May Detect Early Signs of.. My Take on New Ocular Screening Guidelines for Plaquenil.. Multimodal Imaging in Plaquenil Toxicity. Discontinuous bands in the peripheral outer retina can imply hydroxychloroquine toxicity or retinitis pigmentosa. Abnormalities in RPE contour can imply the presence of drusen Figure 3, page 56 or PEDs from CSC. Figure 3. OCT image demonstrating RPE abnormalities consistent with reticular pseudodrusen. Plaquenil is manufactured in only a 200 mg tablet The typical dosage is either 200 or 400 mg per day 200 mg daily puts anyone under 68 pounds at risk1 400 mg of Plaquenil daily puts anyone under 135 pounds at a higher risk for toxicity Therefore, 200mg of Plaquenil daily is going to be a safe dosage for virtually all adults13 Although hydroxychloroquine retinal toxicity is thought to be rare, recent studies suggest it may have a higher prevalence than previously recognized. A large study examining patients with more than 5 years of HCQ use were evaluated with 10-2 visual fields or spectral-domain optical coherence tomography SD OCT.