Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Plaquenil vision changes Chloroquine causes itch mechanism Aplastic anemia is found among people who take Plaquenil, especially for people who are female, 30-39 old, have been taking the drug for 6 - 12 months, also take medication Prednisone, and have Paroxysmal nocturnal haemoglobinuria. What is Plaquenil and what are its benefits for Sjögren’s patients? Plaquenil hydroxychloroquine is a medication that has been used for many years to help musculoskeletal symptoms and fatigue in patients with autoimmune conditions such as rheumatoid arthritis, lupus and Sjögren’s. Hydroxychloroquine Plaquenil is a drug that is classified as an anti-malarial drug. Plaquenil is prescribed for the treatment or prevention of malaria. It is also prescribed for the treatment of rheumatoid arthritis, lupus, and the side effects of lupus such as hair loss, joint pain, and more. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Will plaquenil help anemia Examination of Hydroxychloroquine Use and Hemolytic Anemia in G6PDH., Ask the Expert Plaquenil and Sjögren’s Will plaquenil help cancerChloroquine cancer clinical trials NSAIDs alone didn't help my daughter, but adding 5-Loxin was a game changer for her. Immune cells on the attack produce prostaglandins and leukotrienes and sometimes histamine. Medicines that inhibit these can help slow down the autoimmune response and provide symptom relief while DMARDs like Plaquenil need time to work. Does Plaquenil help with Joint Pain? - Autoimmune diseases.. Hydroxychloroquine Plaquenil Side Effects & Dosage for Malaria. Plaquenil and Anemia - General Discussion - Life With Lupus. Plaquenil is prescribed for the treatment or prevention of malaria. It is also prescribed for the treatment of rheumatoid arthritis, lupus, and the side effects of lupus such as hair loss, joint pain, and more. If any severe blood disorder such as aplastic anemia, agranulocytosis, leukopenia, or thrombocytopenia, appears which is not attributable to the disease under treatment, consider discontinuation of Plaquenil. Plaquenil should be administered with caution in patients having glucose-6-phosphate dehydrogenase G-6-PD deficiency. Plaquenil can cause serious side effects when used in high doses for chronic diseases such as RA over the long term. The New Zealand Dermatological Society recommends that to decrease the risk of retina damage, no more than 200mg of Plaquenil should be taken a day, and a dose of 400mg per day should be taken no longer than a few weeks.