However, the increased use of mefloquine over the past decade has resulted in reports of rare, but severe, neuropsychiatric adverse reactions, such as anxiety, depression, hallucinations and psychosis. A direct causality between mefloquine and severe reactions among travelers has been partly confounded by factors associated with foreign travel and, in the case of therapeutic doses of mefloquine, the central nervous system manifestations of Plasmodium infection itself. Plaquenil bradycardia Chloroquine brand name india Hydroxychloroquine toxicity eye Dose of chloroquine at 4 0 year CHLOROQUINE PSYCHOSIS? Previous Article THE DEMAND FOR PSYCHIATRIC BEDS. Next Article ACUTE GOUTY PERICARDITIS. Article Info Publication History. Published 12. Mefloquine should not be prescribed for prophylaxis in patients with active depression, a recent history of depression, generalized anxiety disorder, psychosis, schizophrenia or other major psychiatric disorders, or with a history of convulsions. Warnings Thank you for your interest in spreading the word about The BMJ. NOTE We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. This report describes an acute exacerbation of neuropsychiatric symptoms after an unwarranted therapeutic dose (1250 mg) of mefloquine in a 37-year-old male previously on a once-a-week prophylactic regimen. The present case provides a unique natural history of mefloquine-induced neuropsychiatric toxicity and revisits its dose-dependent nature. Chloroquine psychosis Chloroquine and Hydroxychloroquine • LITFL • Toxicology., Mefloquine - FDA prescribing information, side effects and. Chloroquine dose for lupus Apr 02, 2019 Chloroquine is rapidly and almost completely absorbed from the gastrointestinal tract, and only a small proportion of the administered dose is found in the stools. Approximately 55% of the drug in the plasma is bound to nondiffusible plasma constituents. Excretion of chloroquine is quite slow, but is increased by acidification of the urine. Aralen Chloroquine Uses, Dosage, Side Effects.. Two Cases of Chloroquine Psychosis The BMJ. PDF Chloroquine psychosis - ResearchGate. Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as. Aug 23, 2006 Convenient once-a-week dosing has made mefloquine a popular choice as malaria prophylaxis for travel to countries with chloroquine-resistant malaria. However, the increased use of mefloquine over the past decade has resulted in reports of rare, but severe, neuropsychiatric adverse reactions, such as anxiety, depression, hallucinations and psychosis. A direct causality between mefloquine and. Our case points out that although chloroquine-induced psychosis is rare, patients presenting with behavioral changes need physicians' attention in order to diagnose early and efficiently treat.