It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes, which transmit the parasites that cause the infection, usually in tropical and subtropical parts of the world. Info plaquenil Btk calcium chloroquine Hydroxychloroquine and lupus Side effects include irritability, headache, weakness, hair lightening or loss, stomach upset, nausea, dizziness, muscle pain, rash and itching. Rarely, hydroxychloroquine can affect the bone marrow leading to reduced white blood cells leukopenia or platelets thrombocytopenia and abnormal red blood cells. Dark spots, hair changes, and muscle weakness. Rarely, hydroxychloroquine can lead to anemia in some individuals. This can happen in individuals with a condition known as G6PD deficiency or porphyria. In rare cases, hydroxychloroquine can cause visual changes or loss of vision. Such vision problems are more Jun 25, 2013 I have PMR, but to get me to try to taper steroids, the rheum started me on generic Plaquenil. My right thigh muscle hurts, and walking up stairs is an issue - I can do it, but it hurts. I am trying to think back to if this was an issue when I was not on the Plaquenil - I have been on it for 4-5 months now, so it's hard to remember. For example, it may be combined with an antibiotic to treat chronic Q-fever, which humans usually catch from farm animals or raw milk. Plaquenil is used to treat other types of infections too. Muscle weakness with plaquenil Plaquenil Oral Uses, Side Effects, Interactions, Pictures., PATIENT FACT SHEET Hydroxychloroquine Plaquenil Plaquenil for sclerodermaPlaquenil dx codeChloroquine resistant falciparum malaria drugs Most patients presented with proximal muscle weakness. A wide range of treatment durations were noted from 4 days to 11 yrs with cumulative daily doses of 1.4 ± 0.96 mg. The toxicity became apparent in the majority of cases after changes in recent disease states such as decline in renal function, initiation of dialysis, or solid organ transplantation. Hydroxychloroquine and Colchicine Induced Myopathy The.. Hydroxychloroquine - thigh muscle weakness?. Plaquenil and muscle weakness Lupus Forums at The Lupus Site. Have you considered that Lupus may be throwing some inflammation your way - ie joint/muscle pain, a Lupus flare - rather than blaming a medication that in general decreases those symptoms? Most of us that have tried stopping plaquenil have found that it was doing more good than we realized, and promptly resumed taking it! In rare cases, Plaquenil can cause cardiomyopathy, a chronic disease of the heart muscle. If you're taking Plaquenil for an autoimmune condition, your symptoms should begin to improve after a few. Symptoms and causes of muscle weakness Muscle weakness myasthenia ranges from a brief bout of weakness to paralysis. Muscle weakness can be the result of a harmless overexertion, but may also be a symptom or the consequence of a serious disorder.