I took plaquenil for a while and it helped to reduce the duration/severity of the flairs, but I still had them. Both these drugs can take up to 3 months to begin to work. Plaqenil didn't stop my flare ups, but did ease some of the symptoms. It might also be worth checking what brand you have, as there are many posts on here about adverse reaction to a cheaper brand. Plaquenil for malaria how Antimalarial plaquenil Aug 23, 2008 It was the opposite for my husband. Imuran was the only thing that made a difference after suffering for over a year. His imuran started at 75 mg purposely along with 40 mg of prednisone. He had a very long slow taper advice from reading many posts on the forum here due to his steroid dependance and off the prednisone as of early Dec. Interaction between Imuran and Plaquenil There is no known interaction between Imuran and Plaquenil in our records. However, an interaction may still exist. Always consult your doctor before taking these medications together. Do not stop taking the medications without a physician's advice. We would like to show you a description here but the site won’t allow us. So it's worth taking some time to think about other possible causes. XBeen taking plaquenil for some 13 years now - seems to reduce the flairs but doesn't stop them. There are many possible triggers for a flare, & as lupus sufferers we are all different. Imuran plaquenil together Drugs & Medications - WebMD, Compare Imuran vs Plaquenil - Comprehensive Analysis by Treato What is the lowest dose of plaquenilPlaquenil 400 mgChloroquine moa sarcoid Does Plaquenil Interact with other Medications? Severe Interactions. These medications are not usually taken together. Consult your healthcare professional e.g. doctor or pharmacist for more in. Plaquenil Oral Interactions with Other Medication. . Side Effects of Imuran Azathioprine, Warnings, Uses. Thanks for taking the time to reply I'm taking Plaquenil for 4 years the Imuran Azathioprine spwas added during the summer. I do feel better today I did come up with the malar rash which is a sure sign that a flair is on the way but as I said I feel better today and the rash is going down. Maybe the Imuran is working. Drug interactions are reported among people who take Plaquenil and Imuran together. This study is created by eHealthMe based on reports of 1,851 people who take Plaquenil and Imuran from Food and Drug Administration FDA, and is updated regularly. On eHealthMe, you can evaluate side effects and drug interactions from 16 million FDA reports. Rheumatoid arthritis is a chronic disorder for which there is no known cure. Fortunately in the last few years, a shift in strategy toward the earlier institution of disease modifying drugs and the availability of new classes of medications have greatly improved the outcomes that can be expected by most patients.