It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes, which transmit the parasites that cause the infection, usually in tropical and subtropical parts of the world. Hydroxychloroquine for lupus nephritis Generalized granuloma annulare hydroxychloroquine In people treated with Plaquenil as a disease-modifying antirheumatic drug, the drug was found to have other beneficial effects. Plaquenil was found to improve lipid profiles, control glucose and reduce the risk of diabetes mellitus, and lower the risk of thrombosis in certain people who are at greater risk. My rheumatologist is reducing my Plaquenil from 400mg to 200mg per day. Does anyone have any experience with reduction in hydroxy? Any bad reaction? How quickly? Many thanks. A lower dose would certainly mean less risk of eye problems in the future, and I’m not even sure how much benefit I’m getting from it. I’m fairly confident that it has helped reduce my joint pain to low levels, but Plaquenil is so slow-acting that it’s hard for me to know exactly what the effects are. For example, it may be combined with an antibiotic to treat chronic Q-fever, which humans usually catch from farm animals or raw milk. Plaquenil is used to treat other types of infections too. Reducing plaquenil Plaquenil Hydroxychloroquine - Side Effects, Dosage., Reducing Plaquenil anyone? My rheumatologist is. - LUPUS UK Side effects of taking plaquenil PLAQUENIL® HYDROXYCHLOROQUINE SULFATE, USP WARNING PHYSICIANS SHOULD COMPLETELY FAMILIARIZE THEMSELVES WITH THE COMPLETE CONTENTS OF THIS LEAFLET BEFORE PRESCRIBING HYDROXYCHLOROQUINE. DESCRIPTION Hydroxychloroquine sulfate is a colorless crystalline solid, soluble in water to at least 20 PLAQUENIL®. Plaquenil toxicity and lowering dosage What You Sjo. Plaquenil Uses, Dosage & Side Effects -. A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including rash, itching/swelling especially of the face/tongue/throat, dizziness, trouble breathing. This is not a complete list of possible side effects. Mar 02, 2013 We propose that hydroxychloroquine will be a practical and safe treatment to reduce synovitis and therefore reduce pain in patients with moderate to severe OA hand symptoms. This will potentially provide a new treatment for OA, which could be of particular use in the primary care setting. Chloroquine has been reported to reduce the bioavailability of praziquantel. Antacids And Kaolin Antacids and kaolin can reduce absorption of chloroquine; an interval of at least 4 hours between intake of these agents and chloroquine should be observed.