Also acts as an inhibitor of autophagy and toll-like receptor (TLR) 7/9. Hydroxychloroquine Sulfate is a potent inhibitor of autophagy. Diagnosis code for plaquenil eye exam Hair loss and plaquenil Cases of long-term use of plaquenil causing low-blood sugar Information on the medication plaquenil Hydroxychloroquine HCQ, sold under the brand name Plaquenil among others, is a medication used for the prevention and treatment of certain types of malaria. Specifically it is used for chloroquine-sensitive malaria. Other uses include treatment of rheumatoid arthritis, lupus, and porphyria cutanea tarda. It is taken by mouth. Please note that the molecular weight for this compound is batch-specific due to variable water content. Packaging Packaged under inert gas Warning Toxicity Harmful C Reconstitution Following reconstitution, aliquot and freeze -20°C. Stock solutions are stable for up to 3 months at -20°C. Hydroxychloroquine sulfate. is 2-4-7-Chloro-4-quinolyl aminopentyl ethylaminoethanol sulfate 11. Its structural formula is The molecular weight of hydroxychloroquine sulfate is 433.95, and molecular formula is. C. 18 H 26 ClN 3 O. H 2 SO 4. PLAQUENIL hydroxychloroquine sulfate tablets contain 200 mg hydroxychloroquine sulfate. HCQ treatment inhibits RCC (renal cell cancer) cell growth, promotes apoptosis, inhibits mitochondrial oxygen consumption, and increases rates of glycolysis In vitro kinase assays: with purified proteins, recombinant S6 protein and recombinant active P70S6K are incubated in 1x kinase buffer with various amount of HCQ or RAD001 in the presence (25 μM) or absence of ATP for 30 minutes at 30°C. It prevents lysosomal acidification, thereby interfering with a key step in the autophagic process. Hydroxychloroquine sulfate molecular weight Hydroxychloroquine sulfate, 98%, ACROS Organics Fisher., Hydroxychloroquine Sulfate - Calbiochem Sigma-Aldrich Plaquenil and acid refux Sep 01, 2019 The molecular weight of hydroxychloroquine sulfate is 433.95, and molecular formula is C 18 H 26 ClN 3 O. H 2 SO 4. Each hydroxychloroquine sulfate tablet intended for oral administration contains 200 mg of hydroxychloroquine sulfate equivalent to 155 mg base. Hydroxychloroquine Tablets - FDA prescribing information.. PLAQUENIL hydroxychloroquine sulfate Label. Hydroxychloroquine SULFATE -. Name Hydroxychloroquine sulfate Drug Entry Hydroxychloroquine. Hydroxychloroquine is a racemic mixture consisting of an R and S enantiomer. 2 Hydroxychloroquine is an aminoquinoline like chloroquine. 8 It is a commonly prescribed medication in the treatment of uncomplicated malaria, rheumatoid arthritis, chronic discoid lupus erythematosus, and systemic lupus erythematosus. 8. AT791 10 µM, E6446 10 µM, Hydroxychloroquine sulfate 40 µM, or chloroquine 40 µM are added to one of the two compartments in pH 5.5 buffer 50 mM NaAce, 15 mM NaCl or pH 7.4 buffer 50 mM KPO 4, 150 mM NaCl, and the plate is incubated at 37°C. The next day, compound concentrations in both chambers are quantitated. Hydroxychloroquine Sulfate is an antimalarial agent used for the treatment of systemic lupus erythematosus, rheumatoid arthritis and other autoimmune, inflammatory and dermatologic conditions. Also acts as an inhibitor of autophagy and toll-like receptor TLR 7/9.