It doesn't go away, but you can keep it under control. It could be triggered by other mouth problems such as having a rough crown or a habit of biting your cheeks or tongue. It’s a long-lasting disease that affects your mouth. It may also be a reaction to metal, such as dental fillings. Sun and plaquenil Plaquenil for arthritis pain Chloroquine phosphate, primarily an antimalarial and amebacidal drug, has been used with considerable success in the treatment of chronic discoid lupus erythematosus 1 and in actinic dermatitis. 2 Because of its efficacy in these dermatoses, it was almost inevitable that it would be used in other dermatoses on an empirical basis. We first became interested in trying it in other dermatoses after using it with considerable benefit in a case of lichen planus. Chloroquine phosphate is used occasionally to decrease the symptoms of rheumatoid arthritis and to treat systemic and discoid lupus erythematosus, scleroderma, pemphigus, lichen planus, polymyositis, sarcoidosis, and porphyria cutanea tarda. Talk to your doctor about the possible risks of using this drug for your condition. Jul 20, 2011 Chemicals or medications associated with development of lichen planus include gold, antibiotics, arsenic, iodides, chloroquine, quinacrine, quinidine, antimony, phenothiazines, diuretics such as chlorothiazide, and many others. Doctors aren't sure what causes oral lichen planus. With oral lichen planus, some doctors believe those cells get confused and attack the lining of your mouth. Other possible triggers include medicines like painkillers, high blood pressure treatments, diabetes drugs, and malaria medications. Lichen planus chloroquine Annular Atrophic Lichen Planus Responds to Hydroxychloroquine., Chloroquine MedlinePlus Drug Information Remove hydroxychloroquine 200 mg tabletPlaquenil and face rashPlaquenil light sensitivityHydroxychloroquine and aspirinPlaquenil liver damage tests Oral lichen planus is a inflammatory condition that affects the inside of the mouth. Signs and symptoms include patches of fine white lines and dots most commonly in the inside of the cheeks, gums, and/or tongue. Most people with lichen planus experience no to few symptoms, others may have painful sores or ulcers in the mouth. Oral lichen planus Genetic and Rare Diseases Information Center GARD.. Oral lichen planus Genetic and Rare Diseases Information.. Lichen planus - Health Diseases & Medical Conditions - AARP. The exact cause of lichen planus is unknown. It may be related to an allergic or immune reaction. Risks for the condition include Exposure to certain medicines, dyes, and other chemicals including gold, antibiotics, arsenic, iodides, chloroquine, quinacrine, quinide, phenothiazines, and diuretics Lichen planus LP is a rare, chronic, inflammatory autoimmune skin and mucous membrane disease. LP most commonly presents as itchy, shiny, reddish-purple spots lesions on the skin cutaneous LP or as white-gray lesions in the mouth or on the lips oral LP. Lichen Planus is found to be an immunologically mediated disease. The exact cause of Lichen Planus is not very clearly understood. Some triggers have been found which are clinically found to be responsible for Lichen Planus. It is one of those conditions where the exact cause remains unknown till the date. There are theories.