Pattern of Retinopathy: Although the locus of toxic damage is parafoveal in many eyes, Asian patients often show an extramacular pattern of damage. Dose: We recommend a maximum daily HCQ use of 5.0 mg/kg real weight, which correlates better with risk than ideal weight. Side effects of plaquenil on eyes Plaquenil toxicity on retina Cheap aralen malaria What is plaquenil eye exam Automated Threshold Visual Field 10-2 White on White SITA Unless patient is of Asian descent “Plaquenil” exam on visual field Red on white visual fields Some clinicians may prefer, however more difficult to interpret due to noisemore sensitive, less specific. Re-test for repeatability of defects. Chloroquine and hydroxychloroquine both belong to the quinolone family and share similar clinical indications and side effects, including retinal toxicity. Chloroquine-induced retinal toxicity was first described in 1959 and the retinal toxic effects of hydroxychloroquine were later described in 1967 3, 4. Plaquenil hydroxychloroquine belongs to a group of medicines called quinolines. Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Risk of Toxicity: The risk of toxicity is dependent on daily dose and duration of use. There are no similar demographic data for CQ, but dose comparisons in older literature suggest using 2.3 mg/kg real weight. Plaquenil visual field asian Plaquenil hydroxychloroquine sulfate dose, indications., Hydroxychloroquine Plaquenil Toxicity and Recommendations. Sle lupus and plaquenilPlaquenil medication oral pigmentation In individuals of Asian descent, retinal toxicity may first be noticed outside the macula. In patients of Asian descent, it is recommended that visual field testing be performed in the central 24 degrees instead of the central 10 degrees. It is recommended that hydroxychloroquine be discontinued if ocular toxicity is suspected and PLAQUENIL hydroxychloroquine sulfate Label. Plaquenil Uses, Dosage & Side Effects -. Recommendations on Screening for Chloroquine and.. Nov 18, 2011 Although visual field defects in HCQ toxicity can be highly variable in terms of the depth of defect, all our patients showed a similar pattern on 10-2 white, with the same areas affected. However, one needs to look carefully for subtle decreases in threshold in the area at risk 2–6 degrees from center. For women, start with 100 pounds, and add 5 pounds for every inch over 5 feet. For men, start with 106 pounds, and add 6 pounds for every inch over 5 feet. The maximum dose of Plaquenil is 6.5 mg/kg of ideal body weight per day, regardless of whether a person is overweight, underweight, or normal weight. Visual field tests take a long time to complete and can be difficult for patients. A traditional 10-2 test takes at least 15 minutes per eye, and if a 24-2 is added, a patient is taking the tests.