I don't get many side effects generally, but with prednisone I DO. It does help, but this can't be a long term affair. Plaquenil is a great drug (I have no experience with it, but many people with lupus take it). I'd ask your rheumy about it and have them explain why they made that choice for you. Prednisone is an intermediate acting corticosteroid-which means it has direct anti-inflamitory properties that take effect begining in a few hours. Is plaquenil another option instead of the prednisone? It is ment to get this undercontrol now and diminish your pain. Will i feel worse before i feel better on plaquenil Corneal pics chloroquine side effects Plaquenil and ambien Long term use of plaquenil Yes, if the plaquenil controls your Lupus flares, it is best to not use the prednisone. I hope you can get off of it completely, or at least take a small maintenance dose. Take it very slow, tapering off, and if you have a reaction, severe fatigue, etc, talk to your doc, about tapering down even slower. So she is having me start sulfasalazine---- do any of you take this and even better do any of you take this along with plaquenil and/or prednisone because until I can wean myself off the awful prednisone I will be taking all three medicines. Interactions between your drugs. There were no interactions found in our database between Plaquenil and prednisone - however, this does not necessarily mean no interactions exist. Always consult with your doctor or pharmacist. It has not direct anti-inflamitory properties and instead works on the immune system-though the mechanism is not known. Plaq is a longer time medication it may take two months before their is a noticable difference. Should you take plaquenil with steroids Methotrexate and plaquenil -, Taking plaquenil and sulfasalazine Arthritis Information Lupus and plaquenil side effectsLithium and plaquenil Medical treatment for lupus has made great strides within the last 50 years. This article will help you understand lupus treatments, lupus medications and side effects, and important lifestyle. Lupus Medications and Treatments. . The Risk of Retinal Toxicity with Plaquenil - Sjogren's. Steroids are taken in different ways, and the dosage may vary depending on the condition you have. The table below gives an idea of how often you might need to take steroids. You should always take medication as prescribed by the person treating you. Tablets, liquids and soluble tablets. Usually once a day. Preferably in the morning. Oct 10, 2003 I was on steroids and plaquenil for 2 years and no one ever told me about how the would contribute to my bone loss thereby causing early onset osteoporosis. I hope you are being closely watched and monitored. Take Plaquenil for the full prescribed length of time for malaria. Your symptoms may improve before the infection is completely cleared. When treating lupus or arthritis, tell your doctor if your symptoms do not improve after 6 months of treatment. Before taking this medicine. You should not use Plaquenil if you are allergic to hydroxychloroquine.