Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. Plaquenil and imuran heat and sun side effects Chloroquine phosphate buy over the counter Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Plaquenil can cause serious side effects when used in high doses for chronic diseases such as RA over the long term. The New Zealand Dermatological Society recommends that to decrease the risk of retina damage, no more than 200mg of Plaquenil should be taken a day, and a dose of 400mg per day should be taken no longer than a few weeks. It appears to be safe treatment for RA in the presence of elective surgery with renal function monitoring 17. Hydroxychloroquine is not considered a potent immunosuppressant, and is therefore typically used perioperatively in orthopedic and other elective surgeries 21. Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Hydroxychloroquine is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Plaquenil and surgery Stopping Plaquenil before surgery Lupus Forums at The., Long-Term Side Effects of Plaquenil for Rheumatoid. Plaquenil age spotsCan plaquenil cause ankle swellingDdo you have to stop plaquenil slowlyPlasmodium falciparum chloroquine resistance RCTs of continuing vs. discontinuing DMARDs at the time of surgery revealed that the risk of infections was not increased, but in fact decreased, when DMARDs were continued, with an RR of 0.39 95% CI 0.17–0.91 37,38. Evidence indicates a low infection risk with these DMARDs in settings other than THA and TKA 39. American College of Rheumatology/American Association.. The Safety of Elective Surgery with Concurrent Use of.. Conditions Plaquenil-related Eye Problems Eugene Eye Care. I saw the dentist today and I have to have a lot of dental work done. I read about Plaquenil and being careful about infection. Anyone have input on this. I guess you have a higher rate of getting an infection? I am 52 and they are also talking about extracting my wisdom teeth surgically. Plaquenil hydroxychloroquine is in a class of drugs called disease-modifying anti-rheumatic drugs, which are used to decrease inflammation, pain and joint damage. While today it is used to treat autoimmune conditions, such as rheumatoid arthritis and lupus, it was originally used as an anti-malaria drug. Hydroxychloroquine is usually taken with food or milk to prevent stomach upset. The dosage and length of treatment are based on your medical condition and response to therapy. In children, dosage is also based on weight.