Hydroxychloroquine is available as the brand-name drug Plaquenil. Generic drugs usually cost less than the brand-name version. Hydroxychloroquine may be used as part of a combination therapy. Typical plaquenil dosage Spell hydroxychloroquin Plaquenil cross eyes Plaquenil heavy legs I was told that Plaquenil can increase your skin's reaction to the sun. All I was told is to make sure I wear sunscreen all the time when I go out because I could burn more easily. So it's good you're using the sunscreen and that you haven't burned. Other potential side effects include but are not limited to nausea, changes in mood, muscle weakness, skin pigmentation and anemia. While the drug may be used during pregnancy, the potential benefits and risks should be discussed with your doctor. In summary, if you have Sjögren’s, hydroxychloroquine may be an option to help your symptoms. Mar 25, 2015 Allergic reaction to Plaquenil. Discussion in 'Medications' started by SickANDexhausted, Mar 25, 2015. SickANDexhausted Junior Member. I was just prescribed Plauqenil and was given Hydroxycloroquine Zydus. Less than two weeks in, I had an extremely bad allergic reaction. Hydroxychloroquine is used to treat lupus erythematosus and rheumatoid arthritis. It isn’t fully understood how this drug works to treat lupus erythematosus or rheumatoid arthritis. That means you may need to take it with other drugs. It treats malaria by killing the parasites that cause the disease. Plaquenil skin reaction Allergic reaction to plaquenil DailyStrength, Ask the Expert Plaquenil and Sjögren’s Lupus weight gain plaquenilSymmetrel plaquenil interactionChloroquine side effectsPlaquenil blurry vision years after stoppingMp biomedicals chloroquine Photosensitivity reaction is found among people who take Plaquenil, especially for people who are female, 50-59 old, have been taking the drug for 6 - 12 months, also take medication Humira, and have Pain Will you have Photosensitivity reaction with Plaquenil.. Allergic reaction to Plaquenil Lupus Forums at The Lupus Site. Plaquenil Uses, Dosage & Side Effects -. Hair bleaching, hair loss, skin pigmentation, rash and itching are recognized skin adverse reactions of plaquenil hydroxychloroquine. These reactions tend to be worse if a patient is taking other medications that have similar skin toxicity. Please consult a dermatologist to ensure skin lesions are not psoriatic because Plaquenil hydroxychloroquine use needs special precautions in psoriasis. If you are taking Plaquenil to treat an inflammatory condition or malaria, you should be aware of the side effects that may occur to your eyes and vision. Plaquenil hydroxychloroquine is in a class of drugs called disease-modifying anti-rheumatic drugs, which are used to decrease inflammation, pain and joint damage. Answer. Plaquenil or hydroxychloroquine has been known to cause a darkened discoloration of skin and/or mucous membranes. This is considered an adverse reaction and should be discussed with your prescriber. It is important to evaluate this color change to make sure there is nothing else wrong.