Some drugs fight inflammation and ease pain, while others help slow disease progression. If there's any comfort in having rheumatoid arthritis these days, it’s that there's a growing number of drugs to deal with its symptoms. Not only can some medications help manage the inflammation, pain, and symptoms of rheumatoid arthritis, but they can stop or slow the progression of the disease, too. Plaquenil false positive Plaquenil skin Commonly used DMARDs include Rheumatrex and Trexall methotrexate sodum, Plaquenil hydroxychloroquine sulfate, Arava leflunomide and Azulfidine sulfasalazine. Pros DMARDs not only help. Commonly used oral DMARDs include methotrexate, sulfasalazine, hydroxychloroquine, low-dose prednisone and a newer agent, leflunomide. Other less commonly used DMARDs include azathioprine, cyclosporin and sodium aurothiomalate intramuscular gold. Biological DMARDS, tumour necrosis factor TNF inhibitors, are discussed below. If a patient is resistant to initial DMARD treatment with an agent such as methotrexate, combination DMARD treatment may be used, adding one or more conventional DMARDs leflunomide, hydroxychloroquine, sulfasalazine or a newer biologic treatment to methotrexate. Treatment guidelines from the American College of Rheumatology (ACR) state that early aggressive treatment is the best way to prevent irreversible joint damage and to maintain quality of life for people with rheumatoid arthritis. Traditionally, rheumatoid arthritis treatments have included a combination of DMARDs, or disease modifying anti-rheumatic drugs, that now include different forms of biologics and two other classes of medications: non-steroidal anti-inflammatory drugs (NSAIDs) and corticosteroids. Dmards plaquenil methotrexate DMARDs Arthritis Foundation, Rheumatoid arthritis, monitoring of DMARDs - BPJ 17 October 2008 Can hydroxychloroquine cause weight gain hair loss Methotrexate, available for over 40 years, is widely used to treat psoriasis and also used to treat cancer. In the 1970s, low-dose methotrexate was prescribed by many rheumatologists to treat rheumatoid arthritis when NSAIDs failed. Methotrexate works faster than other remitting drugs, often bringing improvement in weeks rather than months. Facts About DMARDs Disease-Modifying Anti-Rheumatic Drugs. Traditional Disease-Modifying Anti-Rheumatic Drugs DMARDs. Perioperative Management of Medications Used in the Treatment.. Methotrexate Methotrexate may be sold under the brand names Trexall™, Otrexup ®, Rheumatrex ®, and Rasuvo ®. In addition to being used as a treatment for PsA, methotrexate has been used for decades to treat psoriasis. It helps with pain and swelling, and as a DMARD, it can help slow the progression of the disease. The most commonly used DMARD is methotrexate Trexall®, Rheumatrex®, Otrexup®, Resuvo®. Other DMARDs include sulfasalazine Azulfidine®, leflunomide Arava®, hydroxychloroquine Plaquenil®, Cyclosporine Neoral®, Sandimmune®, Azathioprine Imuran®, and Apremilast Otezla®. Methotrexate. Methotrexate MTX, trade names Trexall™ and Rheumatrex™ is the most commonly used DMARD in the treatment of RA, in up to 80% of patients in some studies. MTX is a folic acid analog, which when administered in high doses blocks purine and pyrimidine synthesis.