Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Method of action of chloroquine Hydroxychloroquine mechanism of action in rheumatoid arthritis Note This document contains side effect information about hydroxychloroquine. Some of the dosage forms listed on this page may not apply to the brand name Plaquenil. For the Consumer. Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some unwanted effects. Yes, Plaquenil causes both weight loss and loss of appetite. Hence, if the loss of appetite and weight loss started after you started on this drug, then yes, it could be due to Plaquenil. However, if you had loss of appetite and weight loss before your started this drug, then the drug can aggravate the process. Both Plaquenil and Tamoxifen can individually cause damage to retina. Taking both drugs at the same time can increase the risk of damage. Can You Take Ibuprofen and Plaquenil Together? Plaquenil has been used safely in combination with salicylates aspirin, non-steroidal anti-inflammatory drugs such as ibuprofen, methotrexate and corticosteroids. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Hydroxychloroquine can suppress appetite How to suppress appetite 10 healthful, evidence-based ways, Plaquenil and loss of appetite - Lupus - MedHelp Plaquenil withdrawlHydroxychloroquine pmrPlaquenil tablet omhuld 200mgDoes hydroxychloroquine cause fatigue Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Hydroxychloroquine Plaquenil. Canada Plaquenil - Canadian Drugs for Rheumatoid Arthritis.. Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus. This is a list of 18 science-based ways to reduce hunger and appetite. Being hungry all the time can make it very difficult to lose weight. Hydroxychloroquine can be taken with a glass of milk or a meal to decrease nausea. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take hydroxychloroquine exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor. What Are the Seven Acupressure Points to Suppress Appetite? By Deborah Green. and by pressing it you can decrease your appetite. Upper Lip. A major control point for appetite suppression is located between the upper lip and the nose. Place your thumb under your upper lip, and your index finger on the outside. Manipulate with some pressure.