Her rheumatologist instructed her to undergo a baseline ocular examination prior to initiating Plaquenil (hydroxychloroquine, Sanofi-Aventis) therapy. Toxic maculopathy associated with chloroquine use was first documented in the literature five decades ago.1 In the United States, Plaquenil––an analog to chloroquine––is used to treat a variety of conditions, including rheumatoid arthritis, lupus and several distinct inflammatory disorders. Although the incidence of macular toxicity is infrequent with Plaquenil use (at a dosage of 200mg or 400mg q.d.), its visual impact can be devastating. Does taking plaquenil cause hair loss Oral plaquenil eye exam Multifocal Electroretinography mfERG Vision Testing. Multifocal ERG has been recognized as an effective test in helping doctors to diagnose and manage diseases affecting the retina, most notably retinal toxicities. 1-3 This visual electrophysiology technique is a test of localized retinal function through quasi-simultaneous stimulation of different areas of the retina. 4 The American Academy. A 57-year-old female presented to the Ophthalmology clinic at UIHC complaining bilateral central photopsias for the past two years. She suffered from Sjogren syndrome and inflammatory arthritis and was currently treated with prednisone and methotrexate. She was previously treated with hydroxychloroquine Plaquenil 200mg bid 6.5mg/kg for 10 years, which was stopped one year prior to. The multifocal electroretinogram multifocal ERG, mfERG provides objective information on localized retinal function to help find early toxic retinopathy. This is Why You Need Multifocal ERG if You Have Plaquenil Patients Initially, central visual acuity may be unaffected, but the patient may notice related paracentral scotomas that often interfere with reading. The associated classic retinal toxicity is described as a bull’s eye maculopathy (ring of depigmented retinal pigment epithelium that spares the foveal area). Mferg plaquenil Electroretinography ERG, Multi-focal Electroretinography., Hydroxychloroquine Plaquenil Toxicity and. How does plaquenil workAralen tabletsJoint task force-bravo chloroquine 1989 What does Plaquenil/hydroxychloroquine do to your eyes? The retina is the film in the back of your eyes. CQ and HCQ can both cause maculopathy or retinopathy. Prior to modern diagnostic techniques, your eye doctor was looking for bull’s eye maculopathy with a dilated exam. Plaquenil - Eye Doctor MD. This is Why You Need Multifocal ERG if You Have Plaquenil.. Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus. Previously diagnosed plaquenil toxicity. Stopped taking drug 7 years prior Vision loss continues to progress Wants to measure change from last exam with mfERG in 2002. Harbors deep seeded anger for old ophthalmologist but seems to like me. Using multifocal ERG ring ratios to detect and follow Plaquenil retinal toxicity A review Review of mfERG ring ratios in Plaquenil toxicity. Don’t Drop Patients on Plaquenil. The other two are multifocal electroretinogram mfERG and fundus autofluorescence FAF. Why the change in the recommendations? Because “the risk of toxicity after years of Plaquenil use is higher than previously believed,” the study says. 1 Also.