These drugs are called disease-modifying antirheumatic drugs (DMARDs), and they are an important part of an overall treatment plan. Disease-modifying drugs act on the immune system to slow the progression of rheumatoid arthritis. This is why they are called "disease-modifying." Many different drugs can be used as DMARDs in the treatment of RA, but some are used more often than others. Plaquenil and alcohol lupus Does plaquenil cure lupus Find patient medical information for Plaquenil Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Hi guys, I was diagnosed with RA in April 08 and I'm 29 years old. My doctor was only able to find it after I requested a MRI of my hands. He believed it was in the very early stages and not extremely bad so prescribed Plaquenil/Hydroxychloroquine since it is the RA drug with the least side. Some common RA medications may also contribute to sleeplessness. One is the steroid prednisone, which can cause insomnia, agitation or depression. Taking it earlier in the day is best, says Dr. Rosian. Another is hydroxychloroquine Plaquenil. It can sometimes causes people to get jumpy, nervous and twitchy. Fragmented Sleep They are not as powerful as other DMARDs, but they usually cause fewer side effects. Hydroxychloroquine (Plaquenil) and sulfasalazine (Azulfidine) are used for mild rheumatoid arthritis. Plaquenil and prednisone for rheumatoid arthritis Prednisone Deltasone, How long did Plaquenil/Hydroxychloroquine take? DailyStrength Chloroquine injection for malaria treatmentAllegra and plaquenilWould chloroquine in a sickle cell patient beh harfmul User Reviews for Plaquenil to treat Rheumatoid Arthritis. The following information is NOT intended to endorse any particular medication. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners. Plaquenil User Reviews for Rheumatoid Arthritis at. Rheumatoid Arthritis and Sleep Arthritis Foundation. Taking Plaquenil for Rheumatoid Arthritis. Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Dosage While in some cases, lower doses of NSAIDS are effective, in rheumatoid arthritis and other forms of inflammatory arthritis a higher dose is often required to decrease inflammation. A lower dosage can initially be used if inflammation is mild, if mechanical pain is the major problem. Many people with rheumatoid arthritis RA can silence their symptoms and halt progression of the disease thanks to biologics, targeted DMARDs and more aggressive treatment approaches. Yet some patients who achieve remission struggle to sustain it. Defining Remission. Remission means different things to different people.