Hydroxychloroquine is available as the brand-name drug Plaquenil. Generic drugs usually cost less than the brand-name version. Hydroxychloroquine may be used as part of a combination therapy. Hydroxychloroquine class Hydroxychloroquine stomach pain Methotrexate may take longer to become effective, but USUALLY, it will take effective within the time frame you're looking at. It took me 6 months to get efficacy settled, and others longer. Take some time to search both drugs, to get a feel for what you're dealing with. Methotrexate Moderate Hydroxychloroquine may reduce the renal clearance of methotrexate; the exact mechanism of this interaction is unknown. The mean AUC of methotrexate was increased 52% and the mean Cmax was reduced 17% when a single dose of methotrexate was given with a dose of hydroxychloroquine 200 mg oral. Methotrexate sodium oral brand names and other generic formulations include Methotrexate Anti-Rheumatic Oral, Rheumatrex Oral, Trexall Oral All generic drug interactions for methotrexate sodium oral lists will include brand and generic names Hydroxychloroquine is used to treat lupus erythematosus and rheumatoid arthritis. It isn’t fully understood how this drug works to treat lupus erythematosus or rheumatoid arthritis. That means you may need to take it with other drugs. It treats malaria by killing the parasites that cause the disease. Can you take hydroxychloroquine with methotrexate Hydroxychloroquine and meloxicam -, Plaquenil hydroxychloroquine sulfate dose, indications. Reddit plaquenilDoes plaquenil give you brittle bonesPlaquenil e malariaSulfasalazine taken with hydroxychloroquinePlaquenil increased appetite Medicines that impair kidney function can increase levels of methotrexate in the body. Taking these medicines in combination with methotrexate increases the risk of bone marrow suppression. Weekly Dose methotrexate, the anti-inflammatory drug that.. Hydroxychloroquine oral and methotrexate sodium oral Drug.. Plaquenil Oral Interactions with Other Medication. Stars. Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Make sure you have a proper meal for dinner not just a snack on the night you're taking it. Drink plenty of water the next day and don't take Folic Acid or a multi-Vitamin which contains Folic Acid on the same day as the MTX because it can intefere with the effect of the MTX. OBJECTIVE To examine the bioavailability of methotrexate MTX in the presence of hydroxychloroquine HCQ, and vice versa, to determine a possible pharmacokinetic explanation for the observation that combination treatment of rheumatoid arthritis with MTX and HCQ has been shown, clinically, to be more potent than MTX used alone.